Cann Compounding-backed research highlights potential of medicinal cannabis for chronic pain, anxiety and PTSD
Cann Compounding is proud to share the results of new Australian research examining the real-world effectiveness and safety of medicinal cannabis for patients living with chronic pain, anxiety and post-traumatic stress disorder (PTSD).
The 12-month Project Twenty21 Australia study, published in Drug Science, Policy and Law, followed 522 patients receiving medicinal cannabis treatment in Australian clinical practice. The study found significant improvements in pain severity, sleep, mood and perceived overall health across the patient groups studied.
As part of its involvement in the research, Cann Compounding supplied CANNC CBD3000 and CANNC CBD5000, high-CBD oil products derived from the cannabis cultivars Charlotte's Web and Charlotte's Angel. Compounded exclusively by Cann Compounding, the CANNC oils were the only strain-specific oils included in the study.
For Cann Compounding, participation in the study reflects an ongoing commitment to supporting research and building the evidence around medicinal cannabis use in Australia.
David Crisci, Founder and CEO of Cann Compounding, said:
“We are very pleased to see the findings of this research published and to have played a role in supporting a study that contributes to the growing evidence base around medicinal cannabis.
“The results reinforce what we have seen through our work with patients and healthcare professionals, while also highlighting the importance of continued research into how medicinal cannabis may support people living with chronic conditions.
“At Cann Compounding, we believe education and evidence are fundamental to improving access and patient care. We will continue to invest in research, education and support to help ensure suitable patients and healthcare professionals have access to reliable information when considering medicinal cannabis as part of their treatment.”
About Cann Compounding
Cann Compounding is an Australian compounding pharmacy specialising in medicinal cannabis formulations. The pharmacy also works alongside patients and healthcare professionals to provide tailored healthcare solutions and education.
Enquiries:
Matthew Soliman matthew@cannhg.com.au
Study: O’Brien K, Beilby J, Lynskey M, et al. Project Twenty21 Australia: Results of a prospective observational study of patients prescribed medicinal cannabis for chronic pain, anxiety and post-traumatic stress disorder. Drug Science, Policy and Law, 2026. doi:10.1177/20503245261475953
O’Brien K, Beilby J, Lynskey M, Barnes M, Schlag A, Nutt D. High cannabidiol oil for the treatment of chronic pain and anxiety: Results from Project Twenty21 Australia. Drug Science, Policy and Law. 2026;12. doi:10.1177/20503245261488438

